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ABOUT ME

As a Biomedical Engineer, my academic work focused on modeling in vivo systems by in vitro means, namely nano and microfludics. I started in Materials Science and quickly became fascinated by biomaterials and artificial human tissues. As an undergraduate, I was exposed to polymer science and  cardiac tissue engineering, which sparked my interest in the applications of cell based therapies and fluid properties of native human tissue. In 2012, I began my PhD at City College of New York focusing on device development for modulating pericellular environments to assess cell behavior and potential therapeutic pathways.  I've worked principally on two systems, CNS cancer cell motility and bone resorption, looking at receptors and pathways implicated in metastasis and osteoporosis, respectively. 

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As a postdoctoral fellow at Albert Einstein College of Medicine beginning in 2018, my aim was pairing oncology research with evaluation of the science funding environment and how to best leverage capital wisely and efficiency for investment in the pressing medical needs of today. This complimented my interest in biotech startup financing and financial modeling.

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In addition to being a practicing engineer, I'm also a life-long athlete and art lover. I'm an avid baseball player and spectator, as well as a recreational landscape photographer and abstract painter.

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Sean McCutCheon, Ph.D.
Biotech Equity Research Associate

Raymond James
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Ph.D. Biomedical Engineering. The City College of New York, 2017.
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B.S. Materials Science and Engineering. The Ohio State University, 2012.
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Select Publications

McCutcheon S*, Stout RJ*, Spray DC. “The dynamic Nexus: Gap junctions control the localization and mobility of other proteins in distinct and surprising ways.” Nature Scientific Reports 2020. doi: 10.1016/j.copsyc.2015.12.009​
 
McCutcheon S, Majeska R, Schaffler M, Vazquez M. “Apoptotic Osteocytes Induce RANKL Production in Bystanders via Purinergic Signaling and Activation of Pannexin Channels.” Journal of Bone and Mineral Research, May 2020, Volume 35, Issue 5, pp 966-977. https://doi.org/10.1002/jbmr.3954.
 
McCutcheon S, Majeska R, Schaffler M, Vazquez M. "A multiscale fluidic device for the study of dendrite-mediated cell to cell communication." Biomedical Microdevices.  2017 Aug 8;19(3):71. doi: 10.1007/s10544-017-0212-1.

McCutcheon S, Unachukwu U, Thakur A, Majeska R, Redenti S, Vazquez M. "In Vitro Formation of Neuroclusters in Microfluidic Devices and Cell Migration as a Function of Stromal-Derived Growth Factor 1 Gradients." Cell Adhesion & Migration. January 2017, Volume 11, Issue 1, pp 1-12. doi: 10.1080/19336918.2015.1131388.
 
Rico-Varela J, Singh T, McCutcheon S, Vazquez M. EGF as a "New Therapeutic Target for Medulloblastoma Metastasis." Cellular and Molecular Bioengineering. December 2015, Volume 8, Issue 4, pp 553–565. doi: 10.1007/s12195-015-0395-6.

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